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Saturday, October 24, 2026● Updated 5:00 PM ET
Medicines & FDA

Personalized mRNA vaccine cuts melanoma's return by 42% in a large trial

Published

A healthcare professional wearing a protective mask and stethoscope

In 1,137 patients whose melanoma had been surgically removed, adding Moderna and Merck's custom-made vaccine to Keytruda lowered the risk of the cancer coming back or death. After two years, 82% were cancer-free versus 70% on Keytruda alone. Full results are being presented this weekend. The vaccine is not yet approved and is available only in clinical trials.

Source: AJMC

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